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People have been talking about this idea that the internet is kind of dead for about 20 years now, and it's starting to feel really true.
Bile Acid biosynthesis in liver and intestinal reabsorption were suppressed under fasting status, whereas refeeding ameliorated the decrease in biosynthesis and reabsorption of BAs due to fasting.
Amazing discussion about dehydration and remission from seizures. I hope this article resonates with you and reaches some people who need it. Dehydration is such an unexplored, but potentially powerful option for so many diseases.
Yet, the participants in the aforementioned study demonstrated normal blood pressure, heart rate, and hemoglobin oxygen saturation, safe values in serum creatinine, urea, K+, Na+, and glucose, a moderate increase in serum osmolality and a substantial increase in glomerular filtration rate.
You can see that by pairing both nutrient deprivation (starvation) and higher sodium levels (hypertonic stress) you get more autophagy expression, however, there seems to be a maximum limit of autophagy at a given time. A threshold and limiting reagent.
You'll notice that a lot of synergies come into play when mixing fasting and psilocybin - Showing us that these insights were long known in ancient Greece, and are attributed to many of the most well respected philosophers.
The deeper you go into a fast, the more sustained and larger stem cell regeneration effects. However, the deeper you go into a fast, the more stress you apply to the body, and it becomes critical to balance it properly. Also the longer you fast the more you activate your quiescent stem cell pool.
While gluconeogenesis can provide glucose during periods of low carbohydrate intake, it may not be sufficient to meet the high energy and substrate demands of stem cells during active regeneration.
When we fast, our body turns to stored fat for energy, a process known as fat oxidation. This isn't just about energy; it's also about water production.
Glycine, a non-essential amino acid, has been studied for its various roles in the body, including its involvement in the process of autophagy, the body's way of cleaning out damaged cells and cell components to make way for new, healthier ones.